Bullied preadolescents have larger right hippocampal volumes than matched non-bullied peers, but this does not mediate cognition¶

Claim · All claims
Evidence · 1 study (2 entries) · associational r2 · q3 · i2 medium
Currency · newest study 2023 · not yet checked against its sources · not reviewed by a person · recheck by 2028: baselines and conditions change

Subclaims¶

q3 i2 Bullied children had larger right hippocampal volumes than non-bullied children (d = 0.52), with no differences in other subcortical volumes. → Menken Miriam S. 2023 q3 i? The larger right hippocampus did not impact any of the three cognition scores and did not act as a mediator. → Menken Miriam S. 2023 (2)

Evidence¶

Menken Miriam S. 2023¶

Menken Miriam S., Rodriguez Rivera Pedro J., Isaiah Amal, Ernst Thomas, Cloak Christine C., Chang Linda. (2023). Longitudinal alterations in brain morphometry mediated the effects of bullying victimization on cognitive development in preadolescents. Developmental Cognitive Neuroscience. https://doi.org/10.1016/j.dcn.2023.101247

q3 · i2 · associational · r2

LMM analysis of FreeSurfer-segmented subcortical volumes in the matched ABCD sample over two visits. The article reports "larger right hippocampal volumes" in bullied children with d = 0.52, and no other subcortical group differences.

"Bullied children had larger right hippocampal volumes than non-bullied children (d=0.52, [95% CI, 0.03–1.01]; P = 0.036) (Fig. 3A, Table S7), but not in any other subcortical brain volumes (P = 0.09–0.96; Table S7)."

Menken Miriam S. 2023 (2)¶

Menken Miriam S., Rodriguez Rivera Pedro J., Isaiah Amal, Ernst Thomas, Cloak Christine C., Chang Linda. (2023). Longitudinal alterations in brain morphometry mediated the effects of bullying victimization on cognitive development in preadolescents. Developmental Cognitive Neuroscience. https://doi.org/10.1016/j.dcn.2023.101247

q3 · i? · associational · r2

Mediation and association analyses testing whether hippocampal volume related to cognition in the same sample. The article reports no impact on Oral Reading Recognition, Processing Speed, or Flanker scores, and the authors state it did not act as a mediator.

"Despite relatively larger right hippocampal volumes in the bullied children, it had no impact on any of the three cognition scores (Oral Reading Recognition: P = 0.43; Pattern Comparison Processing Speed: P = 0.71; Flanker Inhibitory Control and Attention: P = 0.09)"

Discussion¶

Related Claims¶

• Exploratory ROI volume–behavior correlations within SES groups did not survive FDR correction — related
• Bullied preadolescents show larger cortical volumes in left entorhinal, left superior parietal, and right fusiform regions than matched non-bullied peers
• Lower-SES adolescents have smaller hippocampal and DLPFC volumes but do not differ in caudate volumes — related
• Caregiver-reported bullying victimization is associated with higher odds of NSSI/passive suicidality and active suicidality in preadolescent children — related