Children aged 8–11 show significant activation in frontal-striatal-parietal regions during proactive inhibition and striatal activation during reactive inhibition, similar to regions reported in adults¶
Claim · All claims
Evidence · 1 study · associationalr2·q2
Currency · newest study 2021 · not yet checked against its sources · not reviewed by a person · recheck by 2026: baselines and conditions change
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q2 i? One-sample t-tests showed significant activation in the mid frontal cortex, right parietal cortex and right putamen during proactive inhibition, and bilateral striatum activation during reactive inhibition. → Pas P. 2021
Evidence¶
Pas P. 2021¶
Pas P., Hulshoff Pol H.E., Raemaekers M., Vink M. (2021). Self-regulation in the pre-adolescent brain. Developmental Cognitive Neuroscience. https://doi.org/10.1016/j.dcn.2021.101012
q2 · i? · associational · r2
ROI one-sample t-tests in the cohort found significant proactive-inhibition activation surviving Bonferroni correction (p < 0.05/3 = 0.017) in "the mid frontal cortex, t(639) = 9.11; p < 0.001, the right parietal cortex, t(639) = 6.90; p < 0.001, and the right putamen t(639) = 4.42". Reactive inhibition showed significant bilateral striatal activation (left t(639) = 10.67, right t(639) = 10.65, both p < 0.001).
"For proactive inhibition, there was significant activation in the network associated with proactive inhibition: the mid frontal cortex, t(639) = 9.11; p < 0.001, the right parietal cortex, t(639) = 6.90; p < 0.001, and the right putamen t(639) = 4.42; p < 0.001."
Discussion¶
Related Claims¶
- Functional coupling development during inhibition is sex-specific: striatal-motor coupling increases with age in girls, frontostriatal coupling increases with age in boys — related
- Higher self-regulation in pre-adolescent children is associated with stronger right mid frontal cortex activation during proactive inhibition — related
- Self-regulation scores correlate with functional coupling between the right striatum and left motor cortex during reactive inhibition, but not frontostriatal coupling during proactive inhibition — related
- Children show greater inferior frontal gyrus activity than adults during numerical comparisons, while adults show greater left superior parietal activity than children — related
- Children aged 8–11 with higher parent-rated self-regulation show more proactive response slowing on a stop-signal anticipation task — related
Page metadata
| Field | Value |
|---|---|
type |
claim |
id |
children-frontal-striatal-activation-inhibition |
title |
Children aged 8–11 show significant activation in frontal-striatal-parietal regions during proactive inhibition and striatal activation during reactive inhibition, similar to regions reported in adults |
description |
Children aged 8–11 show significant activation in frontal-striatal-parietal regions during proactive inhibition and striatal activation during reactive inhibition, similar to regions reported in adults |
status |
review |
evidence_strength |
moderate |
newest_evidence |
2021 |
recheck_by |
2026 |
generated |
by process:wiki-ingest on 2026-10-17 |
trust |
unverified — no one has confirmed this page's content |
sources |
1 — pas-p-2021 |
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