In the one longitudinal fMRI study, dorsolateral prefrontal engagement reached adult levels by adolescence while dorsal anterior cingulate engagement continued increasing and mediated behavioral improvement¶

Claim · All claims
Evidence · 1 study (2 entries) · review r3 · q2
Currency · newest study 2019 · not yet checked against its sources · not reviewed by a person · overdue for a recheck since 2024: baselines and conditions change

Subclaims¶

q2 i? dlPFC engagement during correct antisaccades was greatest in childhood but at adult levels by adolescence. → Constantinidis Christos 2019 q2 i? dACC engagement increased through adolescence and mediated improvements in antisaccade performance. → Constantinidis Christos 2019 (2)

Evidence¶

Constantinidis Christos 2019¶

Constantinidis Christos, Luna Beatriz. (2019). Neural Substrates of Inhibitory Control Maturation in Adolescence. Trends in Neurosciences. https://doi.org/10.1016/j.tins.2019.07.004

q2 · i? · review · r3

The review reports the single longitudinal fMRI study of inhibitory control, finding childhood-greatest prefrontal engagement and adult-level dlPFC engagement by adolescence; greater prefrontal engagement in children was associated with better performance.

"The one longitudinal fMRI that investigated inhibitory control found that prefrontal engagement when generating correct antisaccades was greatest during childhood, but by adolescence dorsolateral prefrontal cortex (dlPFC) was engaged at adult levels (Fig. 2A–B) [6]."

Constantinidis Christos 2019 (2)¶

Constantinidis Christos, Luna Beatriz. (2019). Neural Substrates of Inhibitory Control Maturation in Adolescence. Trends in Neurosciences. https://doi.org/10.1016/j.tins.2019.07.004

q2 · i? · review · r3

The review reports that dACC activation, correlated with performance and linked to lower antisaccade error rates, increased through adolescence and mediated the effect of age on error rates, supporting a role for immature error processing in adolescent limitations.

"The dorsal anterior cingulate cortex (dACC), which was correlated with performance, showed increasing engagement through adolescence mediating behavioral developmental improvements in AS performance (Fig. 2C–E)."

Discussion¶

Related Claims¶

• Adolescents show adult-level dlPFC beta-band power but lower FEF alpha-band power and weaker dlPFC/FEF beta-alpha cross-frequency coupling during antisaccade preparation — related
• Antisaccade performance follows a curvilinear developmental trajectory best fit by an inverse function, with intra-subject latency variability decreasing with age — related
• Hippocampal engagement during problem solving rises in middle childhood and then decreases to adult-like levels by adolescence — related
• Hippocampal engagement during arithmetic problem solving increases longitudinally in children while prefrontal-parietal engagement decreases — related
• The anterior hippocampus becomes functionally specialized for episodic memory around the transition to adolescence — related
• The ability to generate a single correct inhibitory response is evident early in development, while what improves through adolescence is the proportion of trials with correct inhibitory responses — related
• Monkey neurophysiology shows adolescent-to-adult antisaccade improvement reflects enhanced representation of the goal and vector inversion, not stronger filtering of the stimulus — related
• Preparatory-period baseline activity before the antisaccade stimulus is higher and ramps faster in adult monkeys and predicts correct trials — related
• Impending rewards improve adolescent antisaccade performance toward adult levels, accompanied by greater nucleus accumbens activation — related
• A 10-minute bout of moderate-intensity exercise improves Stroop inhibitory control with increased left dorsolateral prefrontal activation in young adults — related
• Children's ability to shield attention against distraction develops until the second decade of life alongside prefrontal cortex maturation — related