Gene-specific DNA methylation and histone modification are associated with memory formation, as the review reports from Sweatt and colleagues' studies¶
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Evidence · 1 study · reviewr2·q2
Currency · newest study 2016 · not yet checked against its sources · not reviewed by a person
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q2 i? The review attributes to Sweatt and colleagues the demonstration of an association between gene-specific DNA methylation, histone modification and memory formation. → Paul Marshall and Timothy W Bredy 2016
Evidence¶
Paul Marshall and Timothy W Bredy 2016¶
Paul Marshall and Timothy W Bredy. (2016). Cognitive neuroepigenetics: the next evolution in our understanding of the molecular mechanisms underlying learning and memory? npj Science of Learning. https://doi.org/10.1038/npjscilearn.2016.14
q2 · i? · review · r2
Narrative review attributing this finding to Sweatt and colleagues, "who showed an associa- tion between gene-speci fic DNA methylation, histone modi fica- tion and memory formation", building on earlier work by Vanyushin linking DNA methylation to active avoidance and food-seeking in rats. The review reports an association; no effect size is printed.
"These pioneering findings were later rediscovered by Sweatt and colleagues, who showed an associa- tion between gene-speci fic DNA methylation, histone modi fica- tion and memory formation."
Discussion¶
Related Claims¶
- DNMT inhibitors block memory formation and/or consolidation and disrupt well-consolidated memory, implicating DNA methylation in memory processes — related
- Variations in maternal care causally alter DNA methylation at the glucocorticoid receptor promoter with lasting effects on stress reactivity, as the review reports from Meaney and colleagues — related
Page metadata
| Field | Value |
|---|---|
type |
claim |
id |
dna-methylation-histone-modification-associated-memory |
title |
Gene-specific DNA methylation and histone modification are associated with memory formation, as the review reports from Sweatt and colleagues' studies |
description |
Gene-specific DNA methylation and histone modification are associated with memory formation, as the review reports from Sweatt and colleagues' studies |
status |
review |
evidence_strength |
weak |
newest_evidence |
2016 |
generated |
by process:wiki-ingest on 2026-10-26 |
trust |
unverified — no one has confirmed this page's content |
sources |
1 — paul-marshall-and-timothy-w-bredy-2016 |
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