Stress-exposed adolescents show abnormal neural activation in learning- and attention-related regions¶
Claim · All claims
Evidence · 1 study · associationalr2·q3
Currency · newest study 2018 · not yet checked against its sources · not reviewed by a person · overdue for a recheck since 2023: baselines and conditions change
Subclaims¶
Reading the evidence codes
q is the design tier, i the impact, n the sample, and the kind with its r
the rigour judged within that kind: what each code means.
This claim: no standardized effect is recorded in observations/ for it yet, so no benchmark reading is possible.
q3 i? During punished reversal errors, controls showed greater activation than the early stress group in attention-related regions including bilateral middle frontal gyri. → Harms Madeline B. 2018
Evidence¶
Harms Madeline B. 2018¶
Harms Madeline B., Shannon-Bowen Katherine E., Hanson Jamie L., Pollak Seth D. (2018). Instrumental Learning and Cognitive Flexibility Processes are Impaired in Children Exposed to Early Life Stress. Developmental Science. https://doi.org/10.1111/desc.12596
q3 · i? · associational · r2
Whole-brain fMRI ANOVAs (22 stress-exposed, 22 controls) during reversal switch trials revealed group × trial type interactions: "controls showed greater activation than the early stress group in a number of attention-related regions". No group differences emerged during correct hits.
"During incorrect trials that switched from reward to punishment (punished reversal errors), controls showed greater activation than the early stress group in a number of attention-related regions, including bilateral middle frontal gyri, cuneus, and cerebellum"
Discussion¶
Related Claims¶
- ACC activation to reward during reversal is positively associated with reversal learning performance in stress-exposed adolescents — related
- Stress-exposed adolescents learn reward-punishment associations more slowly than controls during acquisition — related
- Stress-exposed adolescents show impaired cognitive flexibility in reversal learning — related
- Stress-exposed adolescents fail to follow the optimal exploratory strategy of initial indiscriminate responding — related
- Lifetime stress severity correlates with poorer learning performance and reduced putamen/ACC activation — related
Page metadata
| Field | Value |
|---|---|
type |
claim |
id |
early-stress-abnormal-learning-neural-activation |
title |
Stress-exposed adolescents show abnormal neural activation in learning- and attention-related regions |
description |
Stress-exposed adolescents show abnormal neural activation in learning- and attention-related regions |
status |
review |
evidence_strength |
moderate |
newest_evidence |
2018 |
recheck_by |
2023 |
generated |
by process:wiki-ingest on 2026-10-17 |
trust |
unverified — no one has confirmed this page's content |
sources |
1 — harms-madeline-b-2018 |
Frontmatter is the page's machine-readable record — see the Schema & Guide.