Long-term FISL increases informational connectivity between the MNS/IFG and social-cognition and reward regions during positive face perception¶

Claim · All claims
Evidence · 1 study · causal r1 · q3
Currency · newest study 2025 · not yet checked against its sources · not reviewed by a person

Subclaims¶

q3 i? After the FISL course, informational connectivity between the MNS and regions including left orbital frontal cortex, amygdala and cingulate gyrus increased during positive vs. neutral face discrimination. → Qi Liu 2025

Evidence¶

Qi Liu 2025¶

Qi Liu, Siyu Zhu, Can Liu, Yanmiao Yang, Chunmei Lan, Xinwei Song, Benjamin Becker, Keith M. Kendrick, Xinqi Zhou & Weihua Zhao. (2025). Neural signals gradually shift towards inferior frontal gyrus and long-term effects following facial imitation-based social learning. npj Science of Learning. https://doi.org/10.1038/s41539-025-00372-9

q3 · i? · causal · r1

fMRI informational connectivity analysis (multi-voxel pattern discrimination time series correlated pairwise) with the MNS and IFG as seed regions during positive vs. neutral face perception: connectivity with orbitofrontal, temporal, cingulate, insula, amygdala and basal ganglia regions "increased after the whole period of repetitive FISL course" (Z > 1.96, permutation p < 0.05, two-tailed).

"the IC between MNS and left orbital frontal cortex (LOFC), right orbital gyrus (ROrG), left precentral gyrus (LPrG), right superior temporal gyrus (RSTG), left precuneus, right insula, right inferior temporal gyrus (RITG), right parahippocampal gyrus (RPhG), left precuneus, left cin- gulate gyrus, left medioventral occipital cortex (LMVOcC), left amyg- dala and basal ganglia increased after the whole period of repetitive FISL course"

Discussion¶

Related Claims¶

• Long-term FISL improves fMRI-based classification of emotional faces but not emotional scenes — related
• Neural pattern similarity within the MNS increases across FISL sessions, more for positive emotions, and tracks behavioral improvement — related
• Information flow within the MNS progressively shifts toward IFG dominance over repeated FISL sessions — related
• Improved positive imitation performance after FISL is mediated by increased MNS neural pattern similarity and MNS–OFC informational connectivity — a narrower finding that bears on this claim
• Encoding L2 words by viewing videos of social situations engages more native-like neural responses than textual translation, and in a second study improved behavioral performance over non-social videos — related