Meta-analyses identify a distributed frontoparietal network for flexible switching including vlPFC, dlPFC, ACC, right AI, parietal and subcortical regions¶

Claim · All claims
Evidence · 1 study · review r2 · q2
Currency · newest study 2015 · not yet checked against its sources · not reviewed by a person · overdue for a recheck since 2020: baselines and conditions change

Subclaims¶

q2 i? Meta-analyses of neuroimaging studies in neurotypical adults identify a distributed network of frontoparietal regions involved in flexible switching. → Dajani 2015

Evidence¶

Dajani 2015¶

Dajani, D. R., & Uddin, L. Q. (2015). Demystifying cognitive flexibility: Implications for clinical and developmental neuroscience. Trends in Neurosciences. https://doi.org/10.1016/j.tins.2015.07.003

q2 · i? · review · r2

Narrative review reporting meta-analytic findings of neuroimaging studies in neurotypical adults. The identified network includes "high-level cortical association areas" such as vlPFC, dlPFC, anterior cingulate and right AI, plus premotor, parietal, inferior temporal, occipital cortex, caudate and thalamus.

"Recent meta-analyses of neuroimaging studies of cognitive flexibility in neurotypical adults have identified a distributed network of frontoparietal regions involved in flexible switching, including high-level cortical association areas"

Discussion¶

Related Claims¶

• The four published neuroimaging studies of cognitive flexibility in ASD report inconsistent activation differences, with altered profiles possibly compensatory — related
• FIR analysis shows adults sustain DLPFC, RLPFC and superior parietal activation for relational integration through later time-bins, whereas children's integration-specific activation appears only in the first time-bins and late DLPFC activation is tied to REL-1 — related
• ASD shows a distinct executive dysfunction profile of impaired cognitive flexibility and planning with intact inhibitory control