Functional connectivity among six task-difficulty-sensitive ROIs classifies HMA versus LMA individuals at 70.49% accuracy, with PI–MCC, HPC–precuneus and TPJ–NAc edges most diagnostic¶

Claim · All claims
Evidence · 1 study · associational r2 · q3
Currency · newest study 2025 · not yet checked against its sources · not reviewed by a person

Subclaims¶

q3 i? A support vector machine trained on PPI functional connectivity among 21 edges between six ROIs distinguished HMA from LMA individuals with 70.49% accuracy, significant by permutation test (p = 0.009). → Jie Liu 2025

Evidence¶

Jie Liu 2025¶

Jie Liu, Zhifeng Li, Jiawang Yang, Hao He & Fang Cui. (2025). The neurocognitive mechanism underlying math avoidance among math anxious people. npj Science of Learning 10:50. https://doi.org/10.1038/s41539-025-00343-0

q3 · i? · associational · r2

PPI functional connectivity was computed in the high minus low task difficulty contrast among six ROIs; a linear SVM with 10-fold cross-validation classified anxiety group. The classifier "successfully distinguished between HMA and LMA individuals with an accuracy of 70.49%", with permutation test p = 0.009.

"A classifier, trained on math anxiety groups utilizing func- tional connectivity features among 21 edges among the six ROIs, success- fully distinguished between HMA and LMA individuals with an accuracy of 70.49%. This classi fication robustness was substantiated through a per- mutation test, repeated5000 times, yielding a significant p-value of 0.009."

Discussion¶

Related Claims¶

• HMA individuals show weaker brain activation discrepancy between high and low task difficulty than LMA peers in valuation and cognitive control regions — related
• Hippocampal, posterior insula and mid-cingulate activation mediate the math anxiety–avoidance relationship via reduced activation discrepancy between difficulties — related
• Task difficulty sensitivity mediates the relationship between math anxiety and math avoidance tendency — related
• HMA individuals show heightened sensitivity to task difficulty but not reward in drift-diffusion modeling of math decisions — related
• Under high task difficulty, HMA individuals accept significantly fewer math problem challenges than LMA individuals, with no group difference under low difficulty — related