Candidate gene polymorphisms (APOE, BDNF, COMT, KIBRA, SERT) are not associated with GPA in older learners¶
Claim · All claims
Evidence · 1 study · associationalr2·q2
Currency · newest study 2017 · not yet checked against its sources · not reviewed by a person
Subclaims¶
Reading the evidence codes
q is the design tier, i the impact, n the sample, and the kind with its r
the rigour judged within that kind: what each code means.
This claim: no standardized effect is recorded in observations/ for it yet, so no benchmark reading is possible.
q2 i? No gene polymorphism was significantly associated with GPA in the initial regression on the genetic subgroup. → Imlach 2017
Evidence¶
Imlach 2017¶
Imlach, A.-R., Ward, D. D., Stuart, K. E., Summers, M. J., Valenzuela, M. J., King, A. E., Saunders, N. L., Summers, J., Srikanth, V. K., Robinson, A. & Vickers, J. C. (2017). Age is no barrier: predictors of academic success in older learners. npj Science of Learning 2:13. https://doi.org/10.1038/s41539-017-0014-5
q2 · i? · associational · r2
In the initial multiple regression on the genetic subgroup (N = 181), none of APOE, BDNF Val66Met, KIBRA, COMT Val158Met or SERT 5-HTTLPR significantly predicted GPA (all p > 0.15 in Table 2). The authors conclude a candidate gene approach to predicting later-life academic success may not succeed.
"as the initial regression identified that no gene polymorphism was significantly associated with GPA, a separate hierarchical multiple linear regression was conducted within the full sample"
Discussion¶
Related Claims¶
- Working memory predicts GPA in the initial model but not the final full-sample model — related
- Full-scale IQ does not predict GPA in older learners — related
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