Hippocampal microstructure continues maturing after early childhood: anterior hippocampus loses mass and posterior hippocampus gains mass from age 4 to 25¶
Claim · All claims
Evidence · 1 study · reviewr3·q2
Currency · newest study 2012 · not yet checked against its sources · not reviewed by a person · overdue for a recheck since 2017: baselines and conditions change
Subclaims¶
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q2 i? A longitudinal structural MRI study found overall hippocampal volume relatively stable after early childhood, with anterior loss and posterior gain from age 4–25. → Ghetti Simona; Bunge Silvia A 2012
Evidence¶
Ghetti Simona; Bunge Silvia A 2012¶
Ghetti Simona; Bunge Silvia A. (2012). Neural Changes Underlying the Development of Episodic Memory During Middle Childhood. Developmental cognitive neuroscience. https://doi.org/10.1016/j.dcn.2012.05.002
q2 · i? · review · r3
Longitudinal structural MRI study (Gogtay et al., 2006, as reviewed) showing regional hippocampal volume changes; the review speculates anterior reductions may reflect synaptic pruning and posterior gains neurogenesis, synaptic elaboration, and/or myelination. The functional significance is stated as unknown.
"while overall hippocampal volume is relatively stable after early childhood, the anterior hippocampus loses mass and the posterior hippocampus gains mass from age 4–25"
Discussion¶
Related Claims¶
- The anterior hippocampus becomes functionally specialized for episodic memory around the transition to adolescence — related
- Hippocampal volume relates to episodic memory differently across development: adults show head/body associations, children show tail associations — related
- Aerobic fitness and diet affect hippocampal volume and predict episodic memory differences, with effects possibly magnified in childhood — related
- Exercise Increases Hippocampal Volume — related
- Early life stress produces structural and functional alterations in prefrontal-hippocampal-amygdala circuits in animals and humans, with reduced hippocampal volume among the most reliable human findings — related
Page metadata
| Field | Value |
|---|---|
type |
claim |
id |
hippocampus-anterior-loss-posterior-gain-age-4-25 |
title |
Hippocampal microstructure continues maturing after early childhood: anterior hippocampus loses mass and posterior hippocampus gains mass from age 4 to 25 |
description |
Hippocampal microstructure continues maturing after early childhood: anterior hippocampus loses mass and posterior hippocampus gains mass from age 4 to 25 |
status |
review |
evidence_strength |
moderate |
newest_evidence |
2012 |
recheck_by |
2017 |
generated |
by process:wiki-ingest on 2026-10-17 |
trust |
unverified — no one has confirmed this page's content |
sources |
1 — ghetti-simona-bunge-silvia-a-2012 |
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