Data-driven parcellation of the pediatric thalamus yields a K = 8 solution with five interpretable thalamic territories¶

Claim · All claims
Evidence · 1 study · associational r2 · q2
Currency · newest study 2026 · not yet checked against its sources · not reviewed by a person

Subclaims¶

q2 i? A K = 8 clustering solution was retained based on spatial compactness, hemispheric symmetry (highest ARI of 0.222), and functional distinctiveness, with five clusters meeting interpretability criteria. → Mino-Matot 2026

Evidence¶

Mino-Matot 2026¶

Mino-Matot, T., Kebiri, H., Jorge, J., Ledoux, J.-B., Fornari, E., Bach Cuadra, M. & Denervaud, S. (2026). Learning environments are associated with age-related differences in thalamocortical attention circuits in childhood. npj Science of Learning, Article in Press. https://doi.org/10.1038/s41539-026-00452-4

q2 · i? · associational · r2

K-means clustering (adapted KNIT pipeline) on voxelwise thalamo-cortical connectivity across the full cohort, with K searched from 3 to 15 using silhouette, Calinski–Harabasz, and Davies–Bouldin metrics. The article reports the ARI of 0.222 for K = 8; the authors note the solution "should be regarded as cohort-specificu n t i l externally replicated".

"Based on spatial compactness, hemispheric symmetry (K = 8 exhibited the highest ARI of 0.222, exceeding all lower-K solutions), and functional distinctiveness, and after considering the quantitative metrics, the K = 8 solution was retained for all subsequent analyses (Fig. 1)."

Discussion¶

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