The strength of the association between polygenic score and educational achievement does not differ across SES groups¶

Claim · All claims
Evidence · 1 study · associational r2 · q2
Currency · newest study 2019 · not yet checked against its sources · not reviewed by a person

Subclaims¶

q2 i? The regression coefficient of EA on PGS was equal across SES groups, i.e., no genotype-by-SES interaction at the level of measured variants. → Eveline L. de Zeeuw 2019

Evidence¶

Eveline L. de Zeeuw 2019¶

Eveline L. de Zeeuw, Kees-Jan Kan, Catharina E. M. van Beijsterveldt, Hamdi Mbarek, Jouke-Jan Hottenga, Gareth E. Davies, Michael C. Neale, Conor V. Dolan and Dorret I. Boomsma. (2019). The moderating role of SES on genetic differences in educational achievement in the Netherlands. npj Science of Learning 4:13. https://doi.org/10.1038/s41539-019-0052-2

q2 · i? · associational · r2

Between-family twin-model regression of EA on PGS within each SES group; the PGS regression coefficient could be equated across groups (Δ−2LL = 2.3, p = 0.517), indicating no moderation of the PGS-EA association by SES.

"the regression coef ficient in the association of educational achievement on PGS did not differ between the SES groups ( Δ−2LL = 2.3, Δdf = 3, p = 0.517)"

Discussion¶

Related Claims¶

• Children in higher SES families have higher average polygenic scores for educational attainment — related
• SES differences in educational achievement persist after accounting for polygenic score differences between children — related