Structural patterns of arithmetic ability correlate with transcriptional profiles enriched for transmembrane transport (subtraction) and synaptic signaling (multiplication)¶
Claim · All claims
Evidence · 1 study · associationalr2·q2
Currency · newest study 2024 · not yet checked against its sources · not reviewed by a person
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Reading the evidence codes
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q2 i? 570 genes positively correlated with the subtraction structural pattern and 212 with the multiplication pattern; enriched processes were transmembrane transport and synaptic signaling respectively. → Zhang 2024
Evidence¶
Zhang 2024¶
Zhang, D., Xie, Y., Wang, L. & Zhou, K. (2024). Structural and transcriptional signatures of arithmetic abilities in children. npj Science of Learning 9, 58. https://doi.org/10.1038/s41539-024-00270-6
q2 · i? · associational · r2
Neuroimaging-transcriptome association analysis using Allen Human Brain Atlas adult post-mortem expression data mapped to arithmetic-related ROIs; gene ontology enrichment showed subtraction-linked genes "primarily involved transmembrane transport" and multiplication-linked genes involved synaptic signaling.
"For subtraction, a total of 570 genes were identified as showing a significant positive correlation (p < 0.05, r > 0). For multiplication, a total of 212 genes were identified as showing a significant positive correlation (p < 0.05, r >0 )."
Discussion¶
Related Claims¶
- When the other operation is not controlled, subtraction models include left IPS and multiplication models include right AG
- A GMV-based model significantly predicts visuospatial working memory, with brain-region overlap with the arithmetic models
Page metadata
| Field | Value |
|---|---|
type |
claim |
id |
transcriptome-signatures-arithmetic-structure |
title |
Structural patterns of arithmetic ability correlate with transcriptional profiles enriched for transmembrane transport (subtraction) and synaptic signaling (multiplication) |
description |
Structural patterns of arithmetic ability correlate with transcriptional profiles enriched for transmembrane transport (subtraction) and synaptic signaling (multiplication) |
status |
review |
evidence_strength |
weak |
newest_evidence |
2024 |
generated |
by process:wiki-ingest on 2026-10-26 |
trust |
unverified — no one has confirmed this page's content |
sources |
1 — zhang-2024 |
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