Ventral striatum response to correct responses scales with working memory load in youth¶
Claim · All claims
Evidence · 1 study · causalr2·q3
Currency · newest study 2012 · not yet checked against its sources · not reviewed by a person
Subclaims¶
Reading the evidence codes
q is the design tier, i the impact, n the sample, and the kind with its r
the rigour judged within that kind: what each code means.
This claim: no standardized effect is recorded in observations/ for it yet, so no benchmark reading is possible.
q3 i? VS activation to correct versus incorrect responses is greater under higher working memory load, driven by the 2-back condition. → Satterthwaite Theodore D. M.D. 2012
Evidence¶
Satterthwaite Theodore D. M.D. 2012¶
Satterthwaite Theodore D. M.D., M.A.; Ruparel Kosha M.S.; Loughead James Ph.D; Elliott Mark A. Ph.D.; Gerraty Raphael T. B.A.; Calkins Monica E. Ph.D.; Hakonarson Hakon M.D. Ph.D.; Gur Ruben C. Ph.D.; Gur Raquel E. M.D., Ph.D.; Wolf Daniel H. M.D., Ph.D. (2012). Being Right Is Its Own Reward: Load and Performance Related Ventral Striatum Activation to Correct Responses During a Working Memory Task in Youth. Neuroimage. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3358426/
q3 · i? · causal · r2
Structurally-defined bilateral VS ROI mixed-model ANOVA in the same 304-subject sample, testing load effects on COR>INCOR signal. Found "greater VS activation seen in association with greater load" [F(2,528)=4.80; p=0.0086].
"In the bilateral ventral striatum, there was a significant effect of working memory load on the correct versus incorrect response, with greater VS activation seen in association with greater load [Figure 3A; F (2, 528)=4.80; p=0.0086]."
Discussion¶
Related Claims¶
- Ventral striatum activation to correct responses peaks in mid-adolescence at approximately age 16 — related
- In youth performing an n-back task without feedback, bilateral ventral striatum activates more strongly to correct than incorrect responses — related
- The VS correct-greater-than-incorrect response is present for both target and foil trials and is not a motor confound — related
- Ventral striatum activation to correct responses is correlated with discrimination performance in youth — related
- Post-error slowing occurs in the 2-back condition despite absence of feedback — related
- Working memory load degrades discrimination accuracy and slows responses in youth — related
Page metadata
| Field | Value |
|---|---|
type |
claim |
id |
vs-response-scales-with-working-memory-load |
title |
Ventral striatum response to correct responses scales with working memory load in youth |
description |
Ventral striatum response to correct responses scales with working memory load in youth |
status |
review |
evidence_strength |
moderate |
newest_evidence |
2012 |
generated |
by process:wiki-ingest on 2026-10-17 |
trust |
unverified — no one has confirmed this page's content |
sources |
1 — satterthwaite-theodore-d-md-2012 |
Frontmatter is the page's machine-readable record — see the Schema & Guide.