Childhood ADHD symptoms are associated with higher late-adolescent depressive symptoms in a population cohort¶

Claim · All claims
Evidence · 1 study (2 entries) · associational r3 · q3
Currency · newest study 2020 · not yet checked against its sources · not reviewed by a person

Subclaims¶

q3 i? Standardised childhood ADHD symptoms predicted continuous adolescent depressive symptom score (b = 0.49, SE = 0.11, p < 0.001). → Powell V 2020 q3 i? Childhood ADHD symptoms predicted clinically significant depressive symptoms at 17.5 years (OR = 1.27, 95% CI 1.15–1.41, p < 0.001). → Powell V 2020 (2)

Evidence¶

Powell V 2020¶

Powell V, Riglin L, Hammerton G, Eyre O, Martin J, Anney R, Thapar A, Rice F. (2020). What explains the link between childhood ADHD and adolescent depression? Investigating the role of peer relationships and academic attainment. European Child & Adolescent Psychiatry. https://doi.org/10.1007/s00787-019-01463-w

q3 · i? · associational · r3

Linear regression in the ALSPAC prospective birth cohort (n = 2950) testing standardised mother-rated DAWBA ADHD symptoms at 7.5 years against SMFQ depressive symptom score at 17.5 years. The article reports "b = 0.49, SE = 0.11, p < 0.001".

"Standardised childhood ADHD symptoms predicted the continuous outcome of adolescent depressive symptom score (b = 0.49, SE = 0.11, p < 0.001)."

Powell V 2020 (2)¶

Powell V, Riglin L, Hammerton G, Eyre O, Martin J, Anney R, Thapar A, Rice F. (2020). What explains the link between childhood ADHD and adolescent depression? Investigating the role of peer relationships and academic attainment. European Child & Adolescent Psychiatry. https://doi.org/10.1007/s00787-019-01463-w

q3 · i? · associational · r3

Logistic regression in the same cohort using the SMFQ clinical cut-point (≥12) at 17.5 years. The article reports "OR = 1.27, 95% CI = 1.15–1.41, p < 0.001".

"Childhood ADHD symptoms predicted the binary outcome of clinically significant depressive symptoms at age 17.5 years (OR = 1.27, 95% CI = 1.15–1.41, p < 0.001)."

Discussion¶

Related Claims¶

• The ADHD–depression association does not significantly differ by sex, though point estimates are slightly stronger in females — related
• Girls with ADHD were rated as having more severe ADHD symptoms than boys with ADHD in this sample — related
• Academic attainment (GCSE results) at age 16 mediates the association between childhood ADHD symptoms and late-adolescent depressive symptoms — related
• Peer problems at age 16 mediate the association between childhood ADHD symptoms and late-adolescent depressive symptoms — related
• Clinical ADHD diagnosis in childhood is associated with increased odds of clinically significant adolescent depressive symptoms — related
• Peer problems at age 9.5 mediate the association between childhood ADHD and depressive symptoms at age 13 — related
• Peer-problem mediation of the ADHD–depression link is not driven entirely by victimisation — a narrower finding that bears on this claim
• At least 15% of children with ADHD continue to meet full diagnostic criteria by age 25 and a further 50% meet criteria in partial remission, with European estimates of persistence up to 80% — related