Children show greater activation for typical than reversed letters in left inferior parietal lobule, left superior temporal gyrus, and early visual regions — the opposite of the adult pattern¶
Claim · All claims
Evidence · 1 study · causalr1·q3
Currency · newest study 2014 · not yet checked against its sources · not reviewed by a person · overdue for a recheck since 2019: baselines and conditions change
Subclaims¶
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q3 i? In the whole-brain fMRI analysis, children showed greater activation for typical than reversed letters in left inferior parietal lobule, left superior temporal gyrus, and early visual regions, while adults had no activation for this contrast; children showed greater activation for reversed letters only in the middle frontal gyrus. → Blackburne LK 2014
Evidence¶
Blackburne LK 2014¶
Blackburne LK, Eddy MD, Kalra P, Yee D, Sinha P, Gabrieli JDE. (2014) Neural Correlates of Letter Reversal in Children and Adults. PLoS ONE 9(5): e98386. https://doi.org/10.1371/journal.pone.0098386
q3 · i? · causal · r1
Whole-brain fMRI analysis of the letter reversal task (15 children, 15 adults) at voxel-wise p <.01 with FDR correction p <.05. Children's reversed-minus-typical activation was negative in phonological and early visual regions, with the sole reversed-greater region being "the middle frontal gyrus"; adults had no activation for the typical-greater contrast. No effect size was printed.
"In children, there was greater activation for typical than reversed letters in left inferior parietal lobule, left superior temporal gyrus, and early visual regions (Figure 4). Children showed greater activation for reversed letters than normal letters in the middle frontal gyrus."
Discussion¶
Related Claims¶
- Adults show significantly greater whole-brain fMRI activation than children for reversed versus typical letters, including left ventral visual stream and bilateral parietal cortices — related
- Adults, but not children, show a differential N170 response to typical versus reversed letters — related
Page metadata
| Field | Value |
|---|---|
type |
claim |
id |
children-greater-activation-typical-letters |
title |
Children show greater activation for typical than reversed letters in left inferior parietal lobule, left superior temporal gyrus, and early visual regions — the opposite of the adult pattern |
description |
Children show greater activation for typical than reversed letters in left inferior parietal lobule, left superior temporal gyrus, and early visual regions — the opposite of the adult pattern |
status |
review |
evidence_strength |
moderate |
newest_evidence |
2014 |
recheck_by |
2019 |
generated |
by process:wiki-ingest on 2026-10-17 |
trust |
unverified — no one has confirmed this page's content |
sources |
1 — blackburne-lk-2014 |
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