Detected slow oscillation amplitude predicts evoked SO amplitude, and detected spindle amplitude predicts evoked spindle amplitude in delayed stimulation, but not cross-band.¶

Claim · All claims
Evidence · 1 study · causal r2 · q3 · i3 large
Currency · newest study 2026 · not yet checked against its sources · not reviewed by a person

Subclaims¶

q3 i3 In the SO condition, detected SO amplitude correlated with evoked SO amplitude (r = 0.73, p < 0.001); in the SPd condition, detected spindle amplitude correlated with evoked spindle amplitude (r = 0.66, p = 0.004). → Jourde 2026 q3 i? Detected SO amplitude did not correlate with evoked spindle activity (r = -0.07, p = 0.78), and detected spindle amplitude did not correlate with evoked slow wave activity in either spindle condition. → Jourde 2026

Evidence¶

Jourde 2026¶

Jourde, H.R., Sita, K.Z., Eyqvelle, Z., Brooks, M., & Coffey, E.B.J. (2026). Modulating sleep: slow oscillation and spindle stimulation effects on physiology and memory. npj Science of Learning. https://doi.org/10.1038/s41539-025-00383-6

q3 · i3 · causal · r2

Correlational analysis of stimulation effectiveness in the nap study found "a significant correlation betweenamplitude ofSOat detection and amplitude of the evoked SO (r = 0.73, p < 0.001)"; a parallel finding held for spindles in the delayed condition (r = 0.66, p = 0.004).

"There was a significant correlation betweenamplitude ofSOat detection and amplitude of the evoked SO (r = 0.73, p < 0.001), suggesting that participants with overall stronger SOs at detection were those who showed stronger evoked SOs."

Discussion¶

Related Claims¶

• Closed-loop auditory stimulation of slow oscillations and spindles evokes significant neurophysiological responses compared to sham in healthy young adults. — related
• Immediate spindle stimulation truncates the stimulated spindle, while delayed stimulation enhances spindle activity without interruption. — related
• Evoked spindle activity showed modest negative correlations with piano task performance changes, while evoked SO strength showed no clear relationship with performance change. — related