Model ablation of engram neurons showed other neurons emerge to support memory, indicating competitive neuronal interactions underlie learning¶

Claim · All claims
Evidence · 1 study · review r1 · q2
Currency · newest study 2016 · not yet checked against its sources · not reviewed by a person

Subclaims¶

q2 i? In modelling studies of the amygdala and perirhinal cortex, ablating neurons that acquired potentiated responses to conditioned stimuli led other neurons to emerge to support memory. → Nair 2016

Evidence¶

Nair 2016¶

Nair, S. S., Paré, D. and Vicentic, A. (2016). Biologically based neural circuit modelling for the study of fear learning and extinction. npj Science of Learning. https://doi.org/10.1038/npjscilearn.2016.15

q2 · i? · review · r1

Simulation-based result the review describes from modelling of the amygdala and perirhinal cortex, where modelers reran simulations after selectively ablating potentiated cells, "effectively going back in time to determine whether they are necessary for learning".

"when ‘engram’neurons are ablated, others emerge to support memory, highlighting the fact that competitive neuronal interactions underlie learning."

Discussion¶

Related Claims¶

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