The GABAB–micro-offline correlation is significantly stronger than the corresponding GABAA (SICI) correlation¶

Claim · All claims
Evidence · 1 study · associational r1 · q3
Currency · newest study 2025 · not yet checked against its sources · not reviewed by a person

Subclaims¶

q3 i? The correlation of GABAB (LICI) with micro-offline performance differed significantly from the GABAA (SICI) correlation with the same measure (Hittner's z = −2.8535, p-value = 0.0043). → Pasquale Cardellicchio & Sara Borgomaneri 2025

Evidence¶

Pasquale Cardellicchio & Sara Borgomaneri 2025¶

Pasquale Cardellicchio & Sara Borgomaneri. (2025). Level of M1 GABAB predicts micro offline consolidation of motor learning during wakefulness. npj Science of Learning 10:10. https://doi.org/10.1038/s41539-025-00299-1

q3 · i? · associational · r1

Dependent-correlation comparison (Hittner's test) in the same 16-participant experiment contrasting the LICI and SICI correlations with micro-offline performance. Only a test statistic is printed ("z = −2.8535, p-value = 0.0043"); no effect size is reported.

"The correlation of GABAB with micro-of fline performance differed signi ficantly from equivalent correlations between GABAA and the same behavioral measure: Hittner's Zp <0 . 0 5(z = −2.8535, p-value = 0.0043)."

Discussion¶

Related Claims¶

• In a Bayesian linear regression, micro-offline-T learning explains a moderate proportion of variance in LICI (R² = 0.69), with moderate evidence for its inclusion — related
• Lower resting GABAB-mediated inhibition in M1 (measured as LICI) is strongly negatively associated with micro-offline motor consolidation gains during early learning — related
• No other neurophysiological measure (MEP, SICI, ICF, sICF) showed a significant correlation with micro-online or micro-offline learning — related