Right insula/IFG intrinsic connectivity is negatively associated with comprehension residuals in resting-state fMRI¶
Claim · All claims
Evidence · 1 study · associationalr2·q2
Currency · newest study 2018 · not yet checked against its sources · not reviewed by a person
Subclaims¶
Reading the evidence codes
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the rigour judged within that kind: what each code means.
This claim: no standardized effect is recorded in observations/ for it yet, so no benchmark reading is possible.
q2 i? ICD beta values in right insula/inferior frontal gyrus were larger for children with negative comprehension residuals (analogous to UPC) than for children with positive residuals, indicating greater density of strong right-hemisphere correlations in UPC. → Li 2018
Evidence¶
Li 2018¶
Li, M., Malins, J. G., DeMille, M. M. C., Lovett, M. W., Truong, D. T., Epstein, K., Lacadie, C., Mehta, C., Bosson-Heenan, J., Gruen, J. R., Frijters, J. C. and the GRaD Study Consortium. (2018). A molecular-genetic and imaging-genetic approach to specific comprehension difficulties in children. npj Science of Learning 3:20. https://doi.org/10.1038/s41539-018-0034-9
q2 · i? · associational · r2
Resting-state fMRI ICD analysis in 58 children from the GRaD sample, controlling for sex, SES, maternal education, and genetic ancestry PCs. The focal relationship remained significant after range restriction (p = .0013) and removing influential points (p = .00015).
"That is, ICD beta values were larger for children with negative comprehension residuals (analogous to UPC) than they were for children with positive comprehension residuals. This result indicates a greater density of strong correlations in the right hemisphere in subjects with UPC compared to UGC."
Discussion¶
Related Claims¶
- Low SES is associated with greater right-hemisphere connectivity in three of four tested network connections — related
- Functional connectivity between right insula/IFG and right SMG is stronger in children with RU2Short alleles — related
Page metadata
| Field | Value |
|---|---|
type |
claim |
id |
right-insula-ifg-icd-negative-comprehension |
title |
Right insula/IFG intrinsic connectivity is negatively associated with comprehension residuals in resting-state fMRI |
description |
Right insula/IFG intrinsic connectivity is negatively associated with comprehension residuals in resting-state fMRI |
status |
review |
evidence_strength |
weak |
newest_evidence |
2018 |
generated |
by process:wiki-ingest on 2026-10-26 |
trust |
unverified — no one has confirmed this page's content |
sources |
1 — li-2018 |
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