RU2-Short correlates negatively with phonological awareness and reading comprehension, and positively with SES, in the overall sample¶

Claim · All claims
Evidence · 1 study · associational r2 · q3
Currency · newest study 2024 · not yet checked against its sources · not reviewed by a person

Subclaims¶

q3 i? The RU2-Short allele was negatively correlated with phonological awareness (r = −0.09, p < 0.01) and reading comprehension (r = −0.08, p < 0.01), and positively correlated with SES (r = 0.08, p < 0.01). → Li 2024

Evidence¶

Li 2024¶

Li, M., DeMille, M. M. C., Lovett, M. W., Bosson-Heenan, J., Frijters, J. C., Gruen, J. R. & the GRaD Study Consortium. (2024). Phonological awareness mediates the relationship between DCDC2 and reading performance with home environment. npj Science of Learning 9, 36. https://doi.org/10.1038/s41539-024-00247-5

q3 · i? · associational · r2

Descriptive correlation analysis (Table 1) across the full GRaD sample of 1419 children; the article states the overall correlations among RU2-Short, moderators, and reading outcomes "tended to be small though significant".

"The RU2-Short allele was negatively correlated with phonological awareness (r = −0.09, p < 0.01) and reading comprehension (r = −0.08, p < 0.01), and was positively correlated with SES ( r = 0.08, p < 0.01)."

Discussion¶

Related Claims¶

• Parental education and SES moderate the relationship between RU2-Short and reading outcomes — related
• Phonological awareness mediates the effect of the DCDC2-READ1 RU2-Short allele on word reading accuracy, word reading fluency, and reading comprehension — related
• The indirect effect of RU2-Short on reading outcomes through phonological awareness is conditional on home environment: significant at low and medium parental education and low SES, but not at high parental education or high SES — related
• The observed gene-by-environment pattern supports the diathesis-stress model over the bioecological model of G × E interaction on reading, in this sample of unrelated children — related