Claims

RU2Short READ1 genotype proportions differ significantly across comprehension groups, highest in UPC

Claim · All claims
Evidence · 1 study · associational r2 · q3
Currency · newest study 2018 · not yet checked against its sources · not reviewed by a person

Subclaims

Reading the evidence codes

q is the design tier, i the impact, n the sample, and the kind with its r the rigour judged within that kind: what each code means.

This claim: no standardized effect is recorded in observations/ for it yet, so no benchmark reading is possible.

q3 i? The proportion of children with at least one RU2Short genotype varied significantly across UPC, EAC, and UGC groups (0.47, 0.37, 0.32; χ2(2) = 10.30, p = 0.006). → Li 2018

Evidence

Li 2018

Li, M., Malins, J. G., DeMille, M. M. C., Lovett, M. W., Truong, D. T., Epstein, K., Lacadie, C., Mehta, C., Bosson-Heenan, J., Gruen, J. R., Frijters, J. C. and the GRaD Study Consortium. (2018). A molecular-genetic and imaging-genetic approach to specific comprehension difficulties in children. npj Science of Learning 3:20. https://doi.org/10.1038/s41539-018-0034-9

q3 · i? · associational · r2

Genetic analysis comparing READ1 genotype frequencies (RU1-1, RU2Long, RU2Short) against the three comprehension groups in the GRaD sample. The χ2 test showed the RU2Short proportion was highest in UPC and lowest in UGC.

"The proportion of the RU2Short genotype signi ficantly varied across the three groups: 0.47 for UPC, 0.37 for EAC, and 0.32 for UGC, χ2(2) = 10.30, p = 0.006."

Discussion

Page metadata
Field Value
type claim
id ru2short-genotype-proportions-vary-comprehension-groups
title RU2Short READ1 genotype proportions differ significantly across comprehension groups, highest in UPC
description RU2Short READ1 genotype proportions differ significantly across comprehension groups, highest in UPC
status review
evidence_strength moderate
newest_evidence 2018
generated by process:wiki-ingest on 2026-10-26
trust unverified — no one has confirmed this page's content
sources 1 — li-2018

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