Listening comprehension shows trait-specific genetic variance beyond the shared genetic factor¶

Claim · All claims
Evidence · 1 study · associational r3 · q2
Currency · newest study 2021 · not yet checked against its sources · not reviewed by a person

Subclaims¶

q2 i? A trait-specific genetic factor for listening comprehension explained 17% (SE = 0.06) of phenotypic variance, corresponding to 56% (SE = 0.14) of its SNP-h2. → Chin Yang Shapland 2021

Evidence¶

Chin Yang Shapland 2021¶

Chin Yang Shapland, Ellen Verhoef, George Davey Smith, Simon E. Fisher, Brad Verhulst, Philip S. Dale and Beate St Pourcain. (2021). Multivariate genome-wide covariance analyses of literacy, language and working memory skills reveal distinct etiologies. npj Science of Learning 6:23. https://doi.org/10.1038/s41539-021-00101-y

q2 · i? · associational · r3

Multi-domain GSEM (passage reading subset, N = 6453): measurement-specific genetic factors for listening comprehension and non-word repetition. The trait-specific factor for listening comprehension explained "17% (SE = 0.06)" of phenotypic variance, i.e. 56% (SE = 0.14) of SNP-h2.

"These factors explained 17% (SE = 0.06) and 12% (SE = 0.05) of the phenotypic variance respectively (Supplementary Table 13 and Fig. 2b), corresponding to 56% (SE = 0.14) and 47% (SE = 0.14) of the SNP-h2"

Discussion¶

Related Claims¶

• Reading fluency, spelling, phonemic awareness, listening comprehension and non-word repetition are moderately heritable (SNP-h2 30–50%) in unrelated youth — related
• Non-word repetition (PWM) shows trait-specific genetic variance beyond the shared genetic factor — related
• Word reading speed carries a trait-specific genetic factor not present for passage reading accuracy — related