Non-word repetition (PWM) shows trait-specific genetic variance beyond the shared genetic factor¶
Claim · All claims
Evidence · 1 study · associationalr3·q2
Currency · newest study 2021 · not yet checked against its sources · not reviewed by a person
Subclaims¶
Reading the evidence codes
q is the design tier, i the impact, n the sample, and the kind with its r
the rigour judged within that kind: what each code means.
This claim: no standardized effect is recorded in observations/ for it yet, so no benchmark reading is possible.
q2 i? A trait-specific genetic factor for non-word repetition explained 12% (SE = 0.05) of phenotypic variance, corresponding to 47% (SE = 0.14) of its SNP-h2. → Chin Yang Shapland 2021
Evidence¶
Chin Yang Shapland 2021¶
Chin Yang Shapland, Ellen Verhoef, George Davey Smith, Simon E. Fisher, Brad Verhulst, Philip S. Dale and Beate St Pourcain. (2021). Multivariate genome-wide covariance analyses of literacy, language and working memory skills reveal distinct etiologies. npj Science of Learning 6:23. https://doi.org/10.1038/s41539-021-00101-y
q2 · i? · associational · r3
Same multi-domain GSEM (passage reading subset, N = 6453): the trait-specific genetic factor for non-word repetition explained "12% (SE = 0.05)" of phenotypic variance, i.e. 47% (SE = 0.14) of SNP-h2.
"These factors explained 17% (SE = 0.06) and 12% (SE = 0.05) of the phenotypic variance respectively (Supplementary Table 13 and Fig. 2b), corresponding to 56% (SE = 0.14) and 47% (SE = 0.14) of the SNP-h2"
Discussion¶
Related Claims¶
- Literacy, phonological awareness, oral language and PWM abilities share a large proportion of underlying genetic variation in unrelated youth — a broader claim this one bears on
- Reading fluency, spelling, phonemic awareness, listening comprehension and non-word repetition are moderately heritable (SNP-h2 30–50%) in unrelated youth — related
- Genetic factors underlying spelling accuracy at age 7 capture nearly all genetic variation in spelling accuracy at age 9 — related
- Listening comprehension shows trait-specific genetic variance beyond the shared genetic factor — related
- Word reading speed carries a trait-specific genetic factor not present for passage reading accuracy — related
- Nonword reading was excluded from the Genomic SEM model because its genetic correlations with word reading and spelling exceeded 1.0 — related
Page metadata
| Field | Value |
|---|---|
type |
claim |
id |
trait-specific-genetic-variance-nonword-repetition |
title |
Non-word repetition (PWM) shows trait-specific genetic variance beyond the shared genetic factor |
description |
Non-word repetition (PWM) shows trait-specific genetic variance beyond the shared genetic factor |
status |
review |
evidence_strength |
moderate |
newest_evidence |
2021 |
generated |
by process:wiki-ingest on 2026-10-26 |
trust |
unverified — no one has confirmed this page's content |
sources |
1 — chin-yang-shapland-2021 |
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