Training improves competence in clozapine management, especially when integrated with clinical experience¶

Claim · All claims
Evidence · 1 study (2 entries) · review r3 · q2
Currency · newest study 2025 · not yet checked against its sources · not reviewed by a person

Subclaims¶

q2 i? Training (online and/or face-to-face) improved competence in clozapine management and reduced time of initiation and early identification of patients with TRS. → Secchi Agostina 2025 q2 i? A clozapine training programme embedded in a community rotation produced significant knowledge improvement (p < 0.001) in a small cohort of 15 trainees after 6 weeks. → Secchi Agostina 2025 (2)

Evidence¶

Secchi Agostina 2025¶

Secchi Agostina, Whiskey Eromona, Nair Sajitha, Shergill Sukhi, Thomas Trudy. (2025). Competence and confidence of health care professionals in using clozapine: a qualitative systematic review and thematic synthesis. Acta Neuropsychiatrica. https://doi.org/10.1017/neu.2025.10024

q2 · i? · review · r3

The review's synthesis of training studies: it reports that training delivered online and/or face-to-face "can improve competence in clozapine management", citing Freudenreich et al. (2013), Cotes et al. (2022) and Oloyede et al. (2023).

"Previous studies have shown how training (online and/or face-to-face) can improve competence in clozapine management (Freudenreich et al., 2013; Cotes et al., 2022; Oloyede et al., 2023), reducing the time of initiation and early identification of patients with TRS."

Secchi Agostina 2025 (2)¶

Secchi Agostina, Whiskey Eromona, Nair Sajitha, Shergill Sukhi, Thomas Trudy. (2025). Competence and confidence of health care professionals in using clozapine: a qualitative systematic review and thematic synthesis. Acta Neuropsychiatrica. https://doi.org/10.1017/neu.2025.10024

q2 · i? · review · r3

The review describes the Freudenreich Clozapine Training Programme, combining face-to-face workshops with weekly participation in a community clozapine clinic, tested on "a small cohort of trainees (n = 15)" with significant knowledge improvement.

"The programme was tested on a small cohort of trainees (n = 15) who showed a significant improvement in general knowledge about clozapine (p < 0.001) after 6 weeks."

Discussion¶

Related Claims¶

• Exposure to clozapine use is associated with higher prescribing rates and better knowledge — related
• Health care professionals show substantial knowledge gaps about clozapine side effects, especially myocarditis and seizures — related
• Professionals self-report competence with clozapine guidelines but express less confidence in adhering to them — related
• Resource mismatch, missing incentives, and discontinuous post-training support constrain the sustainability of training transfer — related
• Higher education, specialised experience, recent training, and seniority are associated with better knowledge, attitudes, and practices. — related