Children with DD show greater brain activation than TD children in parietal, occipito-temporal and prefrontal regions during both addition and subtraction¶

Claim · All claims
Evidence · 1 study · associational r2 · q3
Currency · newest study 2014 · checked against its sources 2026-10-20 (automated, 1 of 1 entry) · not reviewed by a person

Subclaims¶

q3 i? Across both operations, children with DD had greater activity in right IPS, bilateral fusiform gyrus, left lingual gyrus, right visual cortex, and multiple prefrontal regions. → Rosenberg-Lee 2014

Evidence¶

Rosenberg-Lee 2014¶

Rosenberg-Lee, M., Ashkenazi, S., Chen, T., Young, C. B., Geary, D. C., & Menon, V. (2014). Brain hyper-connectivity and operation-specific deficits during arithmetic problem solving in children with developmental dyscalculia. Developmental Science. https://doi.org/10.1111/desc.12216

q3 · i? · associational · r2

Whole-brain block-design fMRI ANOVA main effect of Group in 16 DD and 20 TD children. The study reports "Children with DD had greater activity across operations in the right IPS, the bilateral fusiform gyrus, left lingual gyrus and right visual cortex", plus prefrontal hyperactivation, contrary to predicted under-activation.

"Children with DD had greater activity across operations in the right IPS, the bilateral fusiform gyrus, left lingual gyrus and right visual cortex. In prefrontal cortex, children with DD had greater activity in the right anterior insula and inferior frontal gyrus, bilateral superior frontal gyrus, and right supplementary motor area"

Discussion¶

Learner Variables¶

• Learning Disabilities and Developmental Differences — predictor: learners who differ on it differ in outcomes
• Operations and Place Value — predictor: learners who differ on it differ in outcomes

Related Claims¶

• Correct and incorrect subtraction trials produce similar robust brain activity in DD children, indicating aberrant activation is not driven by error processing — related
• DD children fail to disengage the default mode network during demanding arithmetic, showing aberrant coupling with task-positive IPS regions — related
• DD children show operation-specific hyperactivation: greater IPS, superior parietal lobule and fusiform activity during subtraction, while during addition only the right superior parietal lobule differs (lower in DD) — reports the opposite
• Children with DD show hyper-connectivity, not reduced connectivity, between the IPS and fronto-parietal and default mode networks during arithmetic — related
• Children with developmental dyscalculia are disproportionately impaired on subtraction accuracy relative to addition, showing a significant group × operation interaction — related
• Math achievement correlates with ventral occipital-temporal NRE in both children and adults, with children relying on extrastriate and adults on anterior higher-order visual regions — related
• Neuroimaging shows adults with DD exhibit stronger frontal activations during number semantics, reduced right parietal grey matter, and altered functional connectivity during non-symbolic magnitude comparison — related
• Adults with developmental dyscalculia show reduced left intraparietal activation during serial order processing relative to controls — related
• The putative visual word form area increases activation with presentation rate similarly in both groups, with no group difference or group-by-rate interaction — related
• Adults with dyscalculia show hyper-connectivity between primary visual cortex and inferior occipital cortex and fusiform gyrus — related
• No univariate activation-level differences between adults with dyscalculia and controls during symbolic or non-symbolic number processing — related