The number of genome-wide significant loci associated with educational attainment increases with GWAS discovery sample size¶
Claim · All claims
Evidence · 1 study (2 entries) · reviewr3·q2
Currency · newest study 2017 · not yet checked against its sources · not reviewed by a person
Subclaims¶
Reading the evidence codes
q is the design tier, i the impact, n the sample, and the kind with its r
the rigour judged within that kind: what each code means.
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q2 i? The first GWAS of educational attainment, with 101,069 discovery-sample individuals, identified one significant association with years of schooling. → David Cesarini and Peter M. Visscher 2017
q2 i? A combined analysis of discovery and replication samples (N = 405,072) identified 162 independent loci, a pattern qualitatively similar to medical and anthropometric traits. → David Cesarini and Peter M. Visscher 2017 (2)
Evidence¶
David Cesarini and Peter M. Visscher 2017¶
David Cesarini and Peter M. Visscher. (2017). Genetics and educational attainment. npj Science of Learning 2:4. https://doi.org/10.1038/s41539-017-0005-6
q2 · i? · review · r3
Review of published GWASs: the first GWAS of educational attainment, in a discovery sample of 101,069 individuals, "identified one significant association with years of schooling".
"The first genome-wide association study of educational attainment was conducted in a discovery sample of 101,069 individuals, and identified one significant association with years of schooling."
David Cesarini and Peter M. Visscher 2017 (2)¶
David Cesarini and Peter M. Visscher. (2017). Genetics and educational attainment. npj Science of Learning 2:4. https://doi.org/10.1038/s41539-017-0005-6
q2 · i? · review · r3
Review of the follow-up GWAS: in a combined analysis of discovery and replication samples (N = 405,072), "the number of independent loci further increases to 162", which the review calls qualitatively similar to medical and anthropometric traits.
"In a combined analysis of the discovery and replication samples ( N = 405,072), the number of independent loci further increases to 162. Thus, educational attainment appears to follow a pattern that is qualitatively similar to medical and anthropometric traits."
Discussion¶
Related Claims¶
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Page metadata
| Field | Value |
|---|---|
type |
claim |
id |
education-gwas-loci-increase-with-discovery-sample-size |
title |
The number of genome-wide significant loci associated with educational attainment increases with GWAS discovery sample size |
description |
The number of genome-wide significant loci associated with educational attainment increases with GWAS discovery sample size |
status |
review |
evidence_strength |
moderate |
newest_evidence |
2017 |
generated |
by process:wiki-ingest on 2026-10-27 |
trust |
unverified — no one has confirmed this page's content |
sources |
2 — david-cesarini-and-peter-m-visscher-2017, david-cesarini-and-peter-m-visscher-2017-2 |
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