LTP exhibits electrophysiological properties that make it an attractive candidate memory mechanism, including rapid induction, persistence up to at least a year, and greater persistence with spaced than massed induction protocols¶
Claim · All claims
Evidence · 1 study · reviewr3·q2
Currency · newest study 2019 · not yet checked against its sources · not reviewed by a person
Subclaims¶
Reading the evidence codes
q is the design tier, i the impact, n the sample, and the kind with its r
the rigour judged within that kind: what each code means.
This claim: no standardized effect is recorded in observations/ for it yet, so no benchmark reading is possible.
q2 i? LTP shows rapid induction, long-term maintenance with demonstrated persistence up to at least a year, input specificity, associativity, and regulation by neuromodulators, supporting its role as a memory mechanism. → Wickliffe C. Abraham 2019
Evidence¶
Wickliffe C. Abraham 2019¶
Wickliffe C. Abraham, Owen D. Jones and David L. Glanzman. (2019). Is plasticity of synapses the mechanism of long-term memory storage? npj Science of Learning 4:9. https://doi.org/10.1038/s41539-019-0048-y
q2 · i? · review · r3
Narrative review summarizing key features of LTP from the cited literature. The article states LTP has "a demonstrated capacity for persistence up to at least a year" and "greater persistence with spaced induction protocols than with massed protocols"; LTD shows many of the same properties.
"LTP exhibits numerous electrophysiological properties that make it an attractive candidate memory mechanism: rapid induction, long-term maintenance to varying degrees but with a demonstrated capacity for persistence up to at least a year, 11 greater persistence with spaced induction protocols than with massed protocols"
Discussion¶
Related Claims¶
- Memories can persist and be reinstated in the absence of learning-induced synaptic alterations, supporting cell-intrinsic storage — reports the opposite
- Retrograde intervention experiments—reversing LTP or depotentiating learning-strengthened synapses—cause memory loss, lending strong support to the synaptic plasticity and memory hypothesis — related
- Spaced Practice Improves Retention — related
- Spaced Retrieval Improves Retention — related
- Spacing out retrieval practice produces better long-term retention than massing it — related
- Massed review at end of film produced significantly greater learning than no review or spaced review — related
Page metadata
| Field | Value |
|---|---|
type |
claim |
id |
ltp-properties-attractive-memory-mechanism |
title |
LTP exhibits electrophysiological properties that make it an attractive candidate memory mechanism, including rapid induction, persistence up to at least a year, and greater persistence with spaced than massed induction protocols |
description |
LTP exhibits electrophysiological properties that make it an attractive candidate memory mechanism, including rapid induction, persistence up to at least a year, and greater persistence with spaced than massed inducti... |
status |
review |
evidence_strength |
weak |
newest_evidence |
2019 |
generated |
by process:wiki-ingest on 2026-10-26 |
trust |
unverified — no one has confirmed this page's content |
sources |
1 — wickliffe-c-abraham-2019 |
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