Encoding P3 amplitude is reduced in ADHD adolescents during visual WM encoding, in both early and late time windows¶

Claim · All claims
Evidence · 1 study (2 entries) · associational r2 · q3 · i3 large
Currency · newest study 2020 · not yet checked against its sources · not reviewed by a person

Subclaims¶

q3 i3 The early encoding P3 segment (320–430 ms) showed larger amplitude in the non-ADHD group than in the ADHD group. → Ortega 2020 q3 i3 The late encoding P3 segment (430–600 ms) was also larger in the non-ADHD group, and larger for the Color-Shape condition. → Ortega 2020 (2)

Evidence¶

Ortega 2020¶

Ortega, R., López, V., Carrasco, X., Escobar, M. J., García, A. M., Parra, M. A. & Aboitiz, F. (2020). Neurocognitive mechanisms underlying working memory encoding and retrieval in Attention-Deficit/Hyperactivity Disorder. Scientific Reports 10:7771. https://doi.org/10.1038/s41598-020-64678-x

q3 · i3 · causal · r2

ERP analysis of the encoding period in the EEG session with the same 36 adolescents: the early P3 window "exhibited larger amplitude in the non-ADHD group than in the ADHD", F(1,34)=5.3294, p = 0.02718, η2 = 0.14, with no condition effect or interaction.

"The earlier segment of this component, between 320 to 430 ms, exhibited larger amplitude in the non-ADHD group than in the ADHD (F (1,34)=5.3294, p = 0.02718, η2 = 0.14)"

Ortega 2020 (2)¶

Ortega, R., López, V., Carrasco, X., Escobar, M. J., García, A. M., Parra, M. A. & Aboitiz, F. (2020). Neurocognitive mechanisms underlying working memory encoding and retrieval in Attention-Deficit/Hyperactivity Disorder. Scientific Reports 10:7771. https://doi.org/10.1038/s41598-020-64678-x

q3 · i3 · associational · r2

Same encoding ERP analysis: the late P3 window (430–600 ms) was larger in the non-ADHD group, F(1,34)=6.4352, p = 0.01595, η2 = 0.16, and larger for the Color-Shape condition, F(1,34)=5.8871, p = 0.02071, η2 = 0.15.

"The later part of this positivity (430–600) also showed larger amplitude in the non-ADHD (F(1,34)=6.4352, p = 0.01595, η2 = 0.16), and larger amplitudes for the Color-shape condition (F(1,34)=5.8871, p = 0.02071, η2 = 0.15)."

Discussion¶

Related Claims¶

• Adolescents with ADHD show poorer accuracy than non-ADHD peers on all conditions of a visual short-term memory task, with the largest drop on trials requiring WM updating — related
• Adolescents with ADHD respond more slowly than non-ADHD peers across all conditions, and color-shape binding slows responses in both groups — related
• Retrieval P3 discriminates Same from Different trials only in non-ADHD adolescents, indicating a failure of post-selection prioritization in ADHD — related
• Visual WM binding of color and shape is intact in ADHD: no group differences behaviorally or electrophysiologically, with Bayesian support for null Group x Condition interactions — reports the opposite
• Encoding and retrieval P3 amplitudes are significantly correlated only in non-ADHD adolescents, though the between-group difference in correlations was not statistically discriminative — related