Successful encoding of schema-related information recruits the mPFC whereas successful encoding of schema-unrelated information recruits the medial temporal lobe¶
Claim · All claims
Evidence · 1 study · causalr1·q3
Currency · newest study 2014 · not yet checked against its sources · not reviewed by a person
Subclaims¶
Reading the evidence codes
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q3 i? A Schema × Subsequent Memory interaction showed greater mPFC subsequent memory effects for schema-related than schema-unrelated items, and the opposite pattern in bilateral MTL. → van Kesteren 2014
Evidence¶
van Kesteren 2014¶
van Kesteren, M. T. R., Rijpkema, M., Ruiter, D. J., Morris, R. G. M., & Fernández, G. (2014). Building on Prior Knowledge: Schema-dependent Encoding Processes Relate to Academic Performance. Journal of Cognitive Neuroscience, 26(10), 2250–2261. https://doi.org/10.1162/jocn_a_00630
q3 · i? · causal · r1
fMRI subsequent memory analysis in 31 students during encoding of curriculum-embedded facts. The mPFC showed a positive Congruency × Memory interaction (Z = 3.30, SVC p < .05), and a medial temporal cluster showed the opposite, negative effect for schema-unrelated (correct > incorrect) > schema-related (correct > incorrect).
"The whole-brain analysis (Figure 2A) revealed a positive effect for the Congruency × Memory interaction in the mPFC (peak [MNI 2, 46, 0], Z = 3.30, 27 voxels, SVC for an mPFC mask taken from van Dongen et al., 2011, p < .05) for schema-related (correct > incorrect) > schema-unrelated (correct > incorrect)"
Discussion¶
Related Claims¶
- Encoding reaction times do not differ between schema-related and schema-unrelated trials — related
- mPFC activity during schema-related encoding predicts normalized second-year course grades, with no such relation for MTL activity — related
- Students already show a pretest congruency effect: existing knowledge yields better baseline performance for schema-related questions — related
- New facts related to students' prior disciplinary knowledge are better remembered after 24 hours than schema-unrelated facts — related
Page metadata
| Field | Value |
|---|---|
type |
claim |
id |
schema-by-memory-mpfc-mtl-interaction |
title |
Successful encoding of schema-related information recruits the mPFC whereas successful encoding of schema-unrelated information recruits the medial temporal lobe |
description |
Successful encoding of schema-related information recruits the mPFC whereas successful encoding of schema-unrelated information recruits the medial temporal lobe |
status |
review |
evidence_strength |
moderate |
newest_evidence |
2014 |
generated |
by process:wiki-ingest on 2026-10-17 |
trust |
unverified — no one has confirmed this page's content |
sources |
1 — van-kesteren-2014 |
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