TMR-SD auditory cues presented during sleep did not reliably weaken week-old spatial memories compared to uncued objects¶

Claim · All claims
Evidence · 1 study · causal r1 · q3
Currency · newest study 2024 · not yet checked against its sources · not reviewed by a person

Subclaims¶

q3 i? Cued and uncued week-old object-location memories showed similar forgetting ratios after TMR-SD during an afternoon nap; the difference was not statistically significant. → Nathan W. Whitmore 2024

Evidence¶

Nathan W. Whitmore 2024¶

Nathan W. Whitmore, Erika M. Yamazaki & Ken A. Paller. (2024). Targeted memory reactivation with sleep disruption does not weaken week-old memories. npj Science of Learning 9, 64. https://doi.org/10.1038/s41539-024-00276-0

q3 · i? · causal · r1

Within-subject nap experiment with 18 participants' data in primary analyses; cues were assigned to 37 of 74 objects matched for pre-nap accuracy. The comparison of cued versus uncued forgetting ratios was not significant, with only a trend; mean FR was 0.94 for cued and 0.99 for uncued objects.

"there was a trend for a lower forgetting ratio for cued compared to uncued objects [t(17) = 1.74,p = 0.10]."

Discussion¶

Related Claims¶

• Whether a cue provoked an EEG-scored arousal did not affect the forgetting ratio of cued objects — related
• Sleep-stage durations, sleep fragmentation, and pre- and post-cue EEG band power were not significantly correlated with forgetting of cued items or the TMR-SD effect — related
• The TMR-SD effect did not differ for objects with low versus high pre-nap spatial error, ruling out memory strength as the explanation — related
• The TMR-SD memory effect differed by post-learning delay: memory weakening occurred with a 1-hour delay but not with a 1-week delay — related
• TMR can be used to selectively weaken or promote forgetting of specific memories during sleep — related