Adolescents show increased anterior insula responses specifically to negative reward prediction errors¶
Claim · All claims
Evidence · 1 study · associationalr2·q3
Currency · newest study 2015 · not yet checked against its sources · not reviewed by a person · overdue for a recheck since 2020: baselines and conditions change
Subclaims¶
Reading the evidence codes
q is the design tier, i the impact, n the sample, and the kind with its r
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This claim: no standardized effect is recorded in observations/ for it yet, so no benchmark reading is possible.
q3 i? In the right anterior insula, adolescents showed a significantly increased response to negative RPEs compared to adults, with no significant differences for neutral or positive RPEs. → Hauser 2015
Evidence¶
Hauser 2015¶
Hauser, T. U., Iannaccone, R., Walitza, S., Brandeis, D., & Brem, S. (2015). Cognitive flexibility in adolescence: Neural and behavioral mechanisms of reward prediction error processing in adaptive decision making during development. Neuroimage, 104, 347-354. https://doi.org/10.1016/j.neuroimage.2014.09.018
q3 · i? · associational · r2
Exploratory fMRI analysis binning model-derived RPEs into negative, neutral and positive bins in the significant right aIns cluster. The article reports the group difference was "caused by a significantly increased response to negative RPEs in adolescents" (p < .001); neutral (p = .734) and positive (p = .142) bins were not significantly different. No effect size is printed.
"Post-hoc t-tests of the three bins revealed that the interaction was caused by a significantly increased response to negative RPEs in adolescents compared to adults (t(34) = − 4.08, p < .001, corrected for multiple comparisons, Fig. 3C)."
Discussion¶
Related Claims¶
- Group-by-RPE interaction in the anterior insula without a general group effect in overall activation — related
- Reward prediction errors are positively correlated with putamen, vmPFC, amygdala and posterior cingulate and anticorrelated with aIns, dmPFC and dlPFC — related
- Adolescents learn faster from negative reward prediction errors than adults in probabilistic reversal learning — related
- Adolescents showed a marginally decreased number of punishments before switching in reversal learning — related
- Adolescents and adults perform equally well on the probabilistic reversal learning task overall — related
Page metadata
| Field | Value |
|---|---|
type |
claim |
id |
adolescent-ains-increased-negative-rpe-response |
title |
Adolescents show increased anterior insula responses specifically to negative reward prediction errors |
description |
Adolescents show increased anterior insula responses specifically to negative reward prediction errors |
status |
review |
evidence_strength |
moderate |
newest_evidence |
2015 |
recheck_by |
2020 |
generated |
by process:wiki-ingest on 2026-10-17 |
trust |
unverified — no one has confirmed this page's content |
sources |
1 — hauser-2015 |
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