Group-by-RPE interaction in the anterior insula without a general group effect in overall activation¶
Claim · All claims
Evidence · 1 study · associationalr1·q3
Currency · newest study 2015 · not yet checked against its sources · not reviewed by a person
Subclaims¶
Reading the evidence codes
q is the design tier, i the impact, n the sample, and the kind with its r
the rigour judged within that kind: what each code means.
This claim: no standardized effect is recorded in observations/ for it yet, so no benchmark reading is possible.
q3 i? A repeated measures ANOVA on binned aIns responses revealed a significant RPE effect and a significant group-by-RPE interaction, but no significant group main effect. → Hauser 2015
Evidence¶
Hauser 2015¶
Hauser, T. U., Iannaccone, R., Walitza, S., Brandeis, D., & Brem, S. (2015). Cognitive flexibility in adolescence: Neural and behavioral mechanisms of reward prediction error processing in adaptive decision making during development. Neuroimage, 104, 347-354. https://doi.org/10.1016/j.neuroimage.2014.09.018
q3 · i? · associational · r1
Omnibus repeated measures ANOVA on the binned anterior insula fMRI responses of all 36 participants, with factors group and RPE bin. The article reports a significant RPE effect (F(2,34) = 40.37, p < .001), a significant group-by-RPE interaction (F(2,34) = 4.60, p = .013), and no significant group effect (F(1,34) = 1.77, p = .193).
"The repeated measures ANOVA with factors group (adolescents, adults) and RPE (negative, neutral, positive) revealed a significant RPE-effect (indicating that the aIns is modulated by RPEs across all subjects, F(2,34) = 40.37, p < .001), a significant group-by-RPE interaction (indicating that only some RPE bins differ between groups, F(2,34) = 4.60, p = .013), but no significant group effect (indicating that the group difference was not caused by generally increased or decreased responses across all RPE bins, F(1,34) = 1.77, p = .193)."
Discussion¶
Related Claims¶
- Adolescents show increased anterior insula responses specifically to negative reward prediction errors — related
- Adolescents learn faster from negative reward prediction errors than adults in probabilistic reversal learning — related
- Reward prediction errors are positively correlated with putamen, vmPFC, amygdala and posterior cingulate and anticorrelated with aIns, dmPFC and dlPFC — related
- Adolescents showed a marginally decreased number of punishments before switching in reversal learning — related
- Adolescents and adults perform equally well on the probabilistic reversal learning task overall — related
Page metadata
| Field | Value |
|---|---|
type |
claim |
id |
ains-group-by-rpe-interaction-omnibus |
title |
Group-by-RPE interaction in the anterior insula without a general group effect in overall activation |
description |
Group-by-RPE interaction in the anterior insula without a general group effect in overall activation |
status |
review |
evidence_strength |
moderate |
newest_evidence |
2015 |
generated |
by process:wiki-ingest on 2026-10-17 |
trust |
unverified — no one has confirmed this page's content |
sources |
1 — hauser-2015 |
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