Incremental R2s for offspring genome, genomic component in parental SES, and environmental SES are about 1.5%, 1.5%, and 7.8%, yielding total genomic R2 of 3% and environmental R2 of 7.8%¶

Claim · All claims
Evidence · 1 study · associational r2 · q2
Currency · newest study 2022 · not yet checked against its sources · not reviewed by a person

Subclaims¶

q2 i? Environmental parental SES explains roughly 7.8% of verbal ability variance versus 1.5% for offspring genome and 1.5% for the genomic component in parental SES. → Guang Guo 2022

Evidence¶

Guang Guo 2022¶

Guang Guo, Meng-Jung Lin and Kathleen Mullan Harris. (2022). Socioeconomic and genomic roots of verbal ability from current evidence. npj Science of Learning 7:22. https://doi.org/10.1038/s41539-022-00137-8

q2 · i? · associational · r2

Derived from comparing model R2s in the combined sample: the full model yields R2 of 21.9%; deducting 20.04% (SES + PCAs) gives 1.5% for offspring genome; deducting 12.6% (PGSs + PCAs) gives 9.3% for SES, from which the 1.5% genomic component is subtracted to yield 7.8%.

"The three incremental R2s corresponding to the two PGSs, the genomic component in parental SES, and the environmental component in parental SES are about 1.5%, 1.5%, and 7.8%, respectively. Thus, the total genomic R2 and the total environmental R2 are estimated to be 3% and 7.8%"

Discussion¶

Learner Variables¶

• Socioeconomic Status — predictor: outcomes differ by group: a gap reflecting circumstances and treatment, not a cause

Related Claims¶

• A positive G×E interaction between the education PGS and SES indicates a favorable SES environment enhances the effect of offspring genome — related
• Including SES and offspring genome in the same model reduces the education PGS effect by more than 20% and SES effects by about 10–15%, implying 20–30% of parental SES effects are genomic — related
• Parental SES context significantly and simultaneously predicts youth verbal ability in Add Health, with mother's education the largest SES coefficient — related