Higher fish intake is associated with slower cognitive decline over 5 to 10 years in AREDS2¶

Claim · All claims
Evidence · 1 study · associational r3 · q3
Currency · newest study 2020 · not yet checked against its sources · not reviewed by a person

Subclaims¶

q3 i? In AREDS2, the rate of decline in TICS-M scores over time differed by fish intake quartile (P-interaction = 0.019), with numerically less steep decline in the highest intake quartile. → Keenan Tiarnán D. 2020

Evidence¶

Keenan Tiarnán D. 2020¶

Keenan Tiarnán D., Agrón Elvira, Mares Julie A., Clemons Traci E., van Asten Freekje, Swaroop Anand, Chew Emily Y.; AREDS and AREDS2 Research Groups. (2020). Adherence to a Mediterranean diet and cognitive function in the Age-Related Eye Disease Studies 1 & 2. Alzheimer's & Dementia. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8328271/

q3 · i? · associational · r3

Longitudinal mixed-model analysis in AREDS2 with repeated cognitive assessments at baseline, 2, 4, and 10 years, testing fish intake quartile by study year interaction. The article reports "the decline in TICS-M scores over time was numerically less steep for participants in fish intake quartile 4"; no standardized effect size is printed.

"By regression analyses, the decline in TICS-M scores over time was numerically less steep for participants in fish intake quartile 4 (−0.19 [−0.23, −0.15] per year) versus 1 (−0.28 [−0.33, −0.22])."

Discussion¶

Related Claims¶

• APOE genotype does not modify the association between Mediterranean diet or fish intake and cognitive function — related
• Higher fish intake is associated with lower risk of cognitive impairment in older adults — related
• Higher Mediterranean diet adherence is not associated with slower cognitive decline over 5 to 10 years — related
• Individual aMED components: vegetable, nut, and moderate alcohol intakes show protective associations with cognitive function — related
• Higher Mediterranean diet adherence is associated with lower risk of cognitive impairment in older adults without dementia — related
• Higher Mediterranean diet adherence is associated with higher cognitive test scores, with dose-response associations — related
• The aMED–cognition associations persist after adjustment for education level — related