Higher Mediterranean diet adherence is associated with higher cognitive test scores, with dose-response associations¶

Claim · All claims
Evidence · 1 study (2 entries) · associational r2–r3 · q3
Currency · newest study 2020 · not yet checked against its sources · not reviewed by a person

Subclaims¶

q3 i? In AREDS, aMED tertile 3 participants scored higher on 3MS and composite measures than tertile 1 participants (regression estimates +1.3 and +1.0, P < .0001). → Keenan Tiarnán D. 2020 q3 i? In AREDS2, aMED tertile 3 participants scored higher on TICS-M and composite measures than tertile 1 participants (regression estimates +1.0 and +1.5, P < .0001). → Keenan Tiarnán D. 2020 (2)

Evidence¶

Keenan Tiarnán D. 2020¶

Keenan Tiarnán D., Agrón Elvira, Mares Julie A., Clemons Traci E., van Asten Freekje, Swaroop Anand, Chew Emily Y.; AREDS and AREDS2 Research Groups. (2020). Adherence to a Mediterranean diet and cognitive function in the Age-Related Eye Disease Studies 1 & 2. Alzheimer's & Dementia. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8328271/

q3 · i? · associational · r3

Cross-sectional general linear models in AREDS comparing absolute 3MS and composite scores across aMED tertiles. The article reports "the regression estimates, in aMED tertile 3 (vs 1), were +1.3 (P < .0001) and +1.0 (P < .0001)"; no standardized effect size is printed.

"As regards absolute scores, the regression estimates, in aMED tertile 3 (vs 1), were +1.3 (P < .0001) and +1.0 (P < .0001), respectively Figure 1B."

Keenan Tiarnán D. 2020 (2)¶

Keenan Tiarnán D., Agrón Elvira, Mares Julie A., Clemons Traci E., van Asten Freekje, Swaroop Anand, Chew Emily Y.; AREDS and AREDS2 Research Groups. (2020). Adherence to a Mediterranean diet and cognitive function in the Age-Related Eye Disease Studies 1 & 2. Alzheimer's & Dementia. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8328271/

q3 · i? · associational · r2

Cross-sectional mixed-model regression in AREDS2 comparing TICS-M and composite scores across aMED tertiles. The article reports "equivalent linear regression estimates were +1.0 (P < .0001) and +1.5 (P < .0001)"; no standardized effect size is printed.

"equivalent linear regression estimates were +1.0 (P < .0001) and +1.5 (P < .0001) Figure 1D, respectively"

Discussion¶

Related Claims¶

• Individual aMED components: vegetable, nut, and moderate alcohol intakes show protective associations with cognitive function — related
• APOE genotype does not modify the association between Mediterranean diet or fish intake and cognitive function — related
• Higher Mediterranean diet adherence is associated with lower risk of cognitive impairment in older adults without dementia — related
• Higher Mediterranean diet adherence is not associated with slower cognitive decline over 5 to 10 years — related
• The aMED–cognition associations persist after adjustment for education level — related
• Higher fish intake is associated with slower cognitive decline over 5 to 10 years in AREDS2 — related
• Higher fish intake is associated with lower risk of cognitive impairment in older adults — related