Age at assessment and achievement measure moderate polygenic score predictions of educational achievement; the adjusted pooled estimate rises to ρ = 0.50¶

Claim · All claims
Evidence · 1 study (2 entries) · quant-synthesis r2 · q4 · i3 large
Currency · newest study 2024 · not yet checked against its sources · not reviewed by a person · recheck by 2027: tool and model accuracy changes quickly

Subclaims¶

q4 i3 After accounting for mean age at assessment, achievement measure, and sample ancestry, the pooled achievement association increased to ρ = 0.50 (95% CI 0.39–0.61). → Wilding 2024 q4 i? Predictions were stronger in adolescents than in younger children (mean age β = 0.014, p < 0.001). → Wilding 2024 (2)

Evidence¶

Wilding 2024¶

Wilding, K., Wright, M., & von Stumm, S. (2024). Using DNA to Predict Education: a Meta-analytic Review. Educational Psychology Review. https://doi.org/10.1007/s10648-024-09928-4

q4 · i3 · quant-synthesis · r2

Multiple-moderator meta-regression of achievement estimates including mean age, achievement measure, and ancestry; the pooled estimate "increased to ρ = 0.50, p < 0.001 (95% CI from 0.39 to 0.61)", indicative of a large effect size.

"When added simultaneously to the meta-regression model, the association pooled estimate increased to ρ = 0.50, p < 0.001 (95% CI from 0.39 to 0.61)"

Wilding 2024 (2)¶

Wilding, K., Wright, M., & von Stumm, S. (2024). Using DNA to Predict Education: a Meta-analytic Review. Educational Psychology Review. https://doi.org/10.1007/s10648-024-09928-4

q4 · i? · quant-synthesis · r2

Meta-regression moderator effect of mean age at phenotypic assessment on achievement predictions; significant at p < 0.001, "with polygenic score predictions being stronger in adolescents than in younger children", consistent with age-increasing heritability via gene-environment correlations.

"Mean age of assessment (β = 0.014, p < 0.001, 95% CI from 0.007 to 0.021), with polygenic score predictions being stronger in adolescents than in younger children"

Discussion¶

Related Claims¶

• Polygenic scores show a meta-analytic association of ρ = 0.24 with educational achievement
• Sample ancestry significantly moderates polygenic score predictions of educational attainment, with stronger predictions in European-ancestry samples
• Polygenic score predictions are reduced in African American relative to European ancestry samples, significantly so only for educational attainment — related
• Polygenic score predictions of education strengthen as GWAS discovery sample sizes increase — related
• Polygenic scores based on the Lee et al. (2018) GWAS show a meta-analytic association of ρ = 0.27 with educational attainment — related