Polygenic scores show a meta-analytic association of ρ = 0.24 with educational achievement¶

Claim · All claims
Evidence · 1 study · quant-synthesis r3 · q4 · i2 medium
Currency · newest study 2024 · not yet checked against its sources · not reviewed by a person

Subclaims¶

q4 i2 Across 19 estimates from 10 samples, polygenic scores are positively associated with educational achievement with a pooled ρ = 0.24 (95% CI 0.18–0.30). → Wilding 2024

Evidence¶

Wilding 2024¶

Wilding, K., Wright, M., & von Stumm, S. (2024). Using DNA to Predict Education: a Meta-analytic Review. Educational Psychology Review. https://doi.org/10.1007/s10648-024-09928-4

q4 · i2 · quant-synthesis · r3

Multilevel meta-analysis of polygenic score predictions of educational achievement (school grades and test scores); the pooled estimate was ρ = 0.24, p < 0.001, "reflecting a positive relation that approximates a large effect size". All estimates but one (Rabinowitz et al., 2019) were positive and significant.

"The meta-analytic association between polygenic scores and educational attainment was ρ = 0.24, p < 0.001 (95% CI from 0.18 to 0.30), reflecting a positive relation that approximates a large effect size"

Discussion¶

Related Claims¶

• Age at assessment and achievement measure moderate polygenic score predictions of educational achievement; the adjusted pooled estimate rises to ρ = 0.50
• Polygenic scores based on the Lee et al. (2018) GWAS show a meta-analytic association of ρ = 0.27 with educational attainment
• Polygenic score predictions of education strengthen as GWAS discovery sample sizes increase
• Polygenic score predictions are reduced in African American relative to European ancestry samples, significantly so only for educational attainment — related
• Sample ancestry significantly moderates polygenic score predictions of educational attainment, with stronger predictions in European-ancestry samples — related