Education and cognitive-ability polygenic scores significantly predict verbal ability, with the education PGS far more robust¶
Claim · All claims
Evidence · 1 study · associationalr2·q2
Currency · newest study 2022 · not yet checked against its sources · not reviewed by a person
Subclaims¶
Reading the evidence codes
q is the design tier, i the impact, n the sample, and the kind with its r
the rigour judged within that kind: what each code means.
This claim: no standardized effect is recorded in observations/ for it yet, so no benchmark reading is possible.
q2 i? One SD of the education PGS is associated with 2.27 points of verbal ability and one SD of the ability PGS with 0.44 points in the combined sample. → Guang Guo 2022
Evidence¶
Guang Guo 2022¶
Guang Guo, Meng-Jung Lin and Kathleen Mullan Harris. (2022). Socioeconomic and genomic roots of verbal ability from current evidence. npj Science of Learning 7:22. https://doi.org/10.1038/s41539-022-00137-8
q2 · i? · associational · r2
Multilevel models of verbal ability on the two PGSs without SES (Table 3, combined sample N = 7194; OLS R2 0.126). The article reports the education PGS coefficient of 2.27 and ability PGS coefficient of 0.44, both statistically significant.
"one standard deviation of the education PGS is associated with 2.27 points of verbal ability, and one standard deviation of the ability PGS is associated with 0.44 points of verbal ability"
Discussion¶
Related Claims¶
- A positive G×E interaction between the education PGS and SES indicates a favorable SES environment enhances the effect of offspring genome — related
- Including SES and offspring genome in the same model reduces the education PGS effect by more than 20% and SES effects by about 10–15%, implying 20–30% of parental SES effects are genomic — related
- Polygenic score predictions of education strengthen as GWAS discovery sample sizes increase — a broader claim this one bears on
- Polygenic scores based on the Lee et al. (2018) GWAS show a meta-analytic association of ρ = 0.27 with educational attainment — related
- Polygenic score predictions are reduced in African American relative to European ancestry samples, significantly so only for educational attainment — related
- Parental SES context significantly and simultaneously predicts youth verbal ability in Add Health, with mother's education the largest SES coefficient — related
Page metadata
| Field | Value |
|---|---|
type |
claim |
id |
pgs-predict-verbal-ability |
title |
Education and cognitive-ability polygenic scores significantly predict verbal ability, with the education PGS far more robust |
description |
Education and cognitive-ability polygenic scores significantly predict verbal ability, with the education PGS far more robust |
status |
review |
evidence_strength |
moderate |
newest_evidence |
2022 |
generated |
by process:wiki-ingest on 2026-10-26 |
trust |
unverified — no one has confirmed this page's content |
sources |
1 — guang-guo-2022 |
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